Title

A Programmable $25 Thermal Cycler for PCR

Authors

David F. BetschFollow
Brian S. Blais, Bryant University

Document Type

Article

Comments

Published by Wiley in Biochemistry and Molecular Biology Education Volume 31, Issue 2, pages 113-4.
Bryant users may access this article here.

Publisher

Wiley

Publication Source

Biochemistry and Molecular Biology Education

Abstract

This article describes the construction of a safe, programmable, automatic thermal cycler for PCR that can be easily constructed by persons with basic soldering and mechanical skills for under $25 in parts and a modest computer such as IBM 486, all of which are readily available. The cycler relies on the heating provided by an incandescent light bulb and cooling by simple convection.