Escherichia coli;Morphology;NAG–thiazoline;Lytic transglycosylase;Penicillin-induced lysis;Autolysin
FEMS Microbiology Letters
The β-hexosaminidase inhibitor and structural analog of the putative oxazolium reaction intermediate of lytic transglycosylases, N-acetylglucosamine thiazoline (NAG–thiazoline), was synthesized in 46% overall yield and tested as an inhibitor of Escherichia coli growth. NAG–thiazoline, at concentrations up to 1 mg/ml, was not found to affect the viability of E. coli DH5α.
Recommended CitationReid, Christopher W.; Blackburn, Neil T.; and Clarke, Anthony J., "The Effect of NAG–thiazoline on Morphology and Surface Hydrophobicity of Escherichia Coli" (2004). Science and Technology Faculty Journal Articles. Paper 43.