A Programmable $25 Thermal Cycler for PCR
Document Type Article
Published by The American Society of Biochemistry and Molecular Biology in Biochemistry and Molecular Biology Education; Volume 31, Issue 2, Mar/Apr 2003, Pages 113-114.
This article describes the construction of a safe, programmable, automatic thermal cycler for PCR that can be easily constructed by persons with basic soldering and mechanical skills for under $25 in parts and a modest computer such as IBM 486, all of which are readily available. The cycler relies on the heating provided by an incandescent light bulb and cooling by simple convection.