Lytic transglycosylases;Peptidoglycan;Catalytic mechanism;Bacterial cell walls
International Journal of Biochemistry and Cell Biology
Lytic transglycosylases are an important class of bacterial enzymes that act on peptidoglycan with the same substrate specificity as lysozyme. Unlike the latter enzymes, however, the lytic transglycosylases are not hydrolases but instead cleave the glycosidic linkage between N-actetylmuramoyl and N-acetylglucosaminyl residues with the concomitant formation of a 1,6-anydromuramoyl product.
Recommended CitationScheurwater, Edie; Reid, Christopher W.; and Clarke, Anthony J., "Lytic Transglycosylases: Bacterial Space-making Autolysins" (2008). Science and Technology Faculty Journal Articles. Paper 40.