Title

Role of Arginine Residues in the Active Site of the Membrane-Bound Lytic Transglycosylase B from Pseudomonas Aeruginosa

Document Type

Article

Comments

Published by ACS Publications in Biochemistry Volume 45, pages 2129-2138.

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Publisher

ACS Publications

Publication Source

Biochemistry

Abstract

Lytic transglycosylases cleave the β-(1→4)-glycosidic bond in the bacterial cell wall heteropolymer peptidoglycan between the N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues with the concomitant formation of a 1,6-anhydromuramoyl residue.

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